OCT Academy

Journal Club - Previous

6. Preventing CME in Melanoma post irradiation

What question must you ask this patient if they presented to you?

Journal Club Issue #6

Discussion

On this image, there evidence of peri-papillary exudate and cotton-wool spots. Important questions to ask include a past history of hypertension, diabetes and radiation. This patient was previously treated with radiation (brachytherapy) for a choroidal melanoma.

In today’s journal club we review work published by Carol Shields et al in JAMA Ophthalmology evaluating the effects of intravitreal injection of bevacizumab for the prevention of radiation retinopathy and macular edema.

Visual Outcome at 4 Years Following Plaque Radiotherapy and Prophylactic Intravitreal Bevacizumab (Every 4 Months for 2 Years) for Uveal Melanoma: Comparison With Nonrandomized Historical Control Individuals. JAMA Ophthalmology.

In this journal club's accompanying 13 min. video, Dr. Sharma will review:

  • Learn how to interpret a survival analysis
  • Review signs that suggest a pigmented lesion is a melanoma
  • Review an OCT of a patient with radiation retinopathy
 

Article

Shields CL, Dalvin LA, Chang M, et al. Visual Outcome at 4 Years Following Plaque Radiotherapy and Prophylactic Intravitreal Bevacizumab (Every 4 Months for 2 Years) for Uveal Melanoma: Comparison With Nonrandomized Historical Control Individuals. JAMA Ophthalmol. Published online December 12, 2019. doi:https://doi.org/10.1001/jamaophthalmol.2019.5132

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