Optometry Continuing Education

OCT Academy - Tip of the Week

143. Deep yellow lesion

A 57-year-old presents with blurred vision. Why?

Tip #143


On the surface of the retina, there is a partial separation of the posterior vitreous from the underlying retinal surface. At the fovea, the vitreous is still adherent in an area of vitreomacular adhesion. The external limiting membrane is somewhat attenuated overlying an area of deep retinal hyperreflectivity. This area of hyperreflectivity involves the RPE and outer segments.

The patient was diagnosed with adult vitelliform vitreomacular degeneration.

In this tip's accompanying 20 min. video, Dr. Sharma takes you through additional diagnostic imagery as well as:

  • Recent OCTA findings in this condition
  • Discuss new research into the pathogenesis of AVFMD
Tip #143 Analysis


Deep retinal hyperreflectivity may be indicative of lipofuscin deposition related to AVFMD.

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