OCT Academy

OCT Mastery - Tip of the Week

151. New scotoma and skin laxity

A 70-year-old woman presents with a new scotoma. She also has skin laxity of her neck. Why?

Tip #151


In the deep retina, there is a large area of hyperreflectivity located anterior to Bruch‘s membrane. There is also a loss of the external limiting membrane (ELM) and ellipsoid zone (EZ) overlying this area. An angiogram demonstrated hyperfluorescent areas radiating from the disc (video).

The patient was diagnosed with Pseudoxanthoma Elasticum.

In this tip's accompanying 17 min. video, Dr. Sharma takes you through additional diagnostic imagery as well as:

  • Learn the differential diagnosis of angioid streaks
  • Learn the angiogram correlation to this condition
  • Learn the systemic diseases which can be associated with angioid streaks
Tip #151 Analysis


Hyperreflectivity of the deep retina may be associated with angioid streaks and systemic disease.

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