This 37-year-old man presents for his annual eye exam with 20/20 BCVA but IOP and cup-to-disc ratio that is on the upper limits of normal. Why?

Cornea Coach #15

Analysis

Here, we can see corneal endothelial pigment deposits. This patient was diagnosed with pigment dispersion syndrome (PDS), which is characterized by dense trabecular meshwork (TM) pigmentation, peripheral iris transillumination defects, and corneal endothelial pigment. PDS is caused by rubbing of the posterior iris on the anterior lens zonules.

In the accompanying 3 min. video featuring Dr. Ashley Brissette, assistant professor at Weill Cornell Medicine in New York, you will learn:

  • Learn how to identify pigment dispersion syndrome
  • Review the pathophysiology of pigment dispersion syndrome
  • Understand why it is important to monitor patients with pigment dispersion syndrome
Cornea Coach #15 Analysis

Cornea Coach Tip

Patients with PDS are susceptible to glaucoma due to obstruction of the TM, so it is important to monitor IOP and cup-to-disc ratio to assess for glaucomatous changes.

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